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1-Chloro-3-(2-Hydroxyethoxy)Propan-2-Ol CAS NO 18371-74-9


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CAS No.:18371-74-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Chloro-3-(2-Hydroxyethoxy)Propan-2-Ol is a versatile chlorohydrin ether derivative, valued for its bifunctional reactivity as both an alkylating agent and a polyol precursor. This compound is essential for the synthesis of specialty polymers, surfactants, and pharmaceutical intermediates where controlled etherification and cross-linking are required. It serves as a critical building block for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

  • Pharmaceutical Intermediate: Key synthon for the production of β-blockers, anticholinergics, and other active pharmaceutical ingredients (APIs).
  • Polymer & Resin Modifier: Used as a cross-linking agent and chain extender in epoxy resins, polyurethanes, and specialty coatings to enhance flexibility and adhesion.
  • Surfactant & Emulsifier Synthesis: Serves as a hydrophilic building block for non-ionic surfactants and emulsifiers used in agrochemicals and industrial formulations.
  • Chemical Synthesis Reagent: Employed in organic synthesis for introducing the 2-hydroxyethoxypropyl moiety into target molecules.
  • Liquid Crystal & Electronic Materials: A precursor in the manufacture of components for liquid crystal displays (LCDs) and other electronic materials.

Basic Information

Product Name 1-Chloro-3-(2-Hydroxyethoxy)Propan-2-Ol
CAS No. 18371-74-9
Molecular Formula C5H11ClO3
Molecular Weight 154.59 g/mol
Synonyms 3-Chloro-2-hydroxypropyl 2-hydroxyethyl ether; 2-Hydroxyethyl 3-chloro-2-hydroxypropyl ether; Glycidol chlorohydrin ether; 1-Chloro-3-(2-hydroxyethoxy)-2-propanol; (2-Hydroxyethoxy)methyloxirane; 3-Chloro-1,2-propanediol mono(2-hydroxyethyl) ether; Chlorohydroxypropyl hydroxyethyl ether
EINECS 242-235-9

Quality Control

Our 1-Chloro-3-(2-Hydroxyethoxy)Propan-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, impurities, and physical properties are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. Due to potential moisture sensitivity, the container should be kept tightly sealed when not in use.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Specific Gravity (20°C) 1.20 - 1.25
Refractive Index (20°C) 1.470 - 1.480

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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