Description

Methyl Chlorothiolformate is a versatile and highly reactive organosulfur compound primarily used as a key chemical intermediate in organic synthesis. Its value lies in its ability to act as a thiocarbonyl transfer agent and a precursor for introducing the thiomethylcarbonyl functional group, enabling the synthesis of complex molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries, where it facilitates the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfur heterocycles or thiocarbonyl moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, contributing to novel modes of action.
• Polymer Chemistry: Serves as a modifier or chain-transfer agent in the development of specialty polymers with tailored properties.
• Chemical Research: A valuable reagent in academic and industrial R&D labs for constructing complex molecular architectures, including heterocycles and natural product analogs.
• Ligand and Catalyst Preparation: Employed in the synthesis of sulfur-containing ligands for metal complexes used in catalysis.
• Fine Chemical Production: Integral to the manufacture of dyes, flavors, and fragrances where specific sulfur functionalities are required.

Basic Information

Product Name	Methyl Chlorothiolformate
CAS No.	18369-83-0
Molecular Formula	C2H3ClOS
Molecular Weight	110.56 g/mol
Synonyms	Chloromethyl thioformate; Methyl chloromethanethioate; Methoxycarbonyl chloride, thio-; Thiocarbonylchloridic acid methyl ester; Methyl chlorothioformate; Chloro(methylthio)methanone; Methyl chlorosulfenylformate; S-Methyl chlorothioformate
EINECS	Contact for details

Quality Control

Our Methyl Chlorothiolformate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (IR, NMR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, oxidizing agents, and moisture. Due to its reactivity as a strong acid/organic solvent, secondary containment is recommended. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 2.0% (total)
Density (at 20°C)	1.30 - 1.35 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.