Description

5-(4-Chlorophenyl)-3H-Furan-2-One is a versatile organic intermediate characterized by its furanone core substituted with a chlorophenyl group. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development teams for constructing active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Serves as a key building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the chlorophenyl-furanone structure.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, aromatic structure.
• Organic Synthesis & Catalysis: Employed as a substrate or ligand in catalytic reactions and as a model compound in methodological studies for constructing heterocyclic frameworks.
• Fine Chemical Production: Acts as an intermediate for dyes, pigments, and other performance chemicals requiring specific chlorinated aromatic motifs.

Basic Information

Product Name	5-(4-Chlorophenyl)-3H-Furan-2-One
CAS No.	18338-90-4
Molecular Formula	C10H7ClO2
Molecular Weight	194.61 g/mol
Synonyms	5-(4-Chlorophenyl)furan-2(3H)-one; 5-(p-Chlorophenyl)-3H-furan-2-one; 4-Chlorophenyl-2-oxo-2,5-dihydrofuran; 2(3H)-Furanone, 5-(4-chlorophenyl)-; 5-(4-Chlorophenyl)-2(3H)-furanone; p-Chlorophenylbutenolide; 4'-Chloro-2,3-dihydrobenzofuran-5-one (tautomeric form).
EINECS	Contact for details

Quality Control

Our 5-(4-Chlorophenyl)-3H-Furan-2-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.