Description

(3R)-2,3,4,5,6,7,8,8Aβ-Octahydro-6β-Hydroxy-3β,6,8-Trimethyl-1H-3Aα,7α-Methanoazulene-8α-Carboxylic Acid is a high-purity, complex sesquiterpene carboxylic acid derivative, serving as a critical chiral intermediate and building block in advanced organic synthesis. Its unique fused ring structure and stereochemistry make it valuable for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical and fine chemical sectors, particularly those working on novel active pharmaceutical ingredients (APIs), natural product derivatives, and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including anti-inflammatory and antiviral compounds.
• Fine Chemical Synthesis: Used as a sophisticated building block in the multi-step synthesis of complex natural products and specialty chemicals.
• Asymmetric Catalysis Research: Employed in the study and development of new chiral ligands and catalysts due to its defined stereocenters.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing specific sesquiterpenoid aroma compounds.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in organic and medicinal chemistry.
• Agrochemical Research: Investigated as an intermediate for developing new, structurally complex bioactive molecules.

Basic Information

Product Name	(3R)-2,3,4,5,6,7,8,8Aβ-Octahydro-6β-Hydroxy-3β,6,8-Trimethyl-1H-3Aα,7α-Methanoazulene-8α-Carboxylic Acid
CAS No.	18319-38-5
Molecular Formula	C15H22O3
Molecular Weight	250.33 g/mol
Synonyms	8α-Carboxy-6β-hydroxy-3β,6,8-trimethyl-1,2,3,4,5,6,7,8,8aβ,3aα,7aα-perhydro-3aα,7aα-methanoazulene; (3R,3aR,6R,7aS,8aS)-6-Hydroxy-3,6,8-trimethyl-1,2,3,3a,4,5,6,7,7a,8,8a,8b-dodecahydroazuleno[4,5-b]furan-8-carboxylic acid; 6β-Hydroxy-3β,6,8-trimethyl-1,2,3,4,5,6,7,8,8aβ,3aα,7aα-perhydro-3aα,7aα-methanoazulene-8α-carboxylic acid; A Sesquiterpene Carboxylic Acid Derivative; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our (3R)-2,3,4,5,6,7,8,8Aβ-Octahydro-6β-Hydroxy-3β,6,8-Trimethyl-1H-3Aα,7α-Methanoazulene-8α-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, strength, and purity. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.