Description

1-(Trimethylsilyloxy)-Ethoxyethene Ethylacetate-Trimethylsilylenol Ether is a specialized organosilicon reagent, specifically a silyl enol ether derivative, widely used as a versatile synthon in advanced organic synthesis. Its primary value lies in its ability to act as a protected enolate equivalent, enabling controlled carbon-carbon bond formation under mild conditions. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it facilitates the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly for introducing ketone or aldehyde functionalities via controlled alkylation or aldol reactions.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where precise stereochemistry and functional group manipulation are required.
• Fine Chemical Manufacturing: Serves as a critical reagent for the production of flavors, fragrances, dyes, and other high-value specialty chemicals.
• Academic & Industrial R&D: Employed in research laboratories for methodological development, total synthesis of natural products, and exploration of new reaction pathways in organic chemistry.
• Material Science Precursor: Potential use in the synthesis of silicon-containing polymers or hybrid organic-inorganic materials.

Basic Information

Product Name	1-(Trimethylsilyloxy)-Ethoxyethene Ethylacetate-Trimethylsilylenol Ether
CAS No.	18295-66-4
Molecular Formula	C9H20O3Si
Molecular Weight	204.34 g/mol
Synonyms	Ethyl 1-(Trimethylsilyloxy)vinyl Ether; 1-Ethoxy-1-(trimethylsilyloxy)ethene; Ethyl (1-(Trimethylsilyloxy)vinyl) Ether; Ethyl 1-(Trimethylsilyloxy)ethenolate; Trimethylsilyl Ethyl Ketene Acetal; TMS Ethyl Ketene Acetal; Silyl Enol Ether Derivative; 18295-66-4
EINECS	Contact for details

Quality Control

Our 1-(Trimethylsilyloxy)-Ethoxyethene Ethylacetate-Trimethylsilylenol Ether is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.