Description

5-Trimethylsilyl-2-Furoic Acid is a high-purity organosilicon derivative of furoic acid, serving as a versatile and valuable building block in advanced organic synthesis. Its primary value lies in its dual functionality, where the silyl group acts as a protective moiety and the carboxylic acid provides a handle for further derivatization, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, especially in medicinal chemistry programs targeting heterocyclic compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its unique heterocyclic structure.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialized polymers and silicon-containing advanced materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide bond formations where a protected or modified furan moiety is required.
• Chemical Research & Development: A critical reagent in academic and industrial R&D labs for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	5-Trimethylsilyl-2-Furoic Acid
CAS No.	18292-14-3
Molecular Formula	C8H12O3Si
Molecular Weight	184.26 g/mol
Synonyms	2-Furoic acid, 5-(trimethylsilyl)-; 5-(Trimethylsilyl)furan-2-carboxylic acid; 5-TMS-2-furoic acid; Trimethyl(5-carboxy-2-furyl)silane; 5-Trimethylsilylfuran-2-carboxylic Acid; 18292-14-3; 5-(Trimethylsilyl)-2-furancarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Trimethylsilyl-2-Furoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.