Description

1-Bromo-3,4-Dichlorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its ability to undergo selective cross-coupling reactions, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-purity intermediate for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex diaryl or aryl-heteroaryl structures.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where its halogen substituents allow for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine ligands and organometallic catalysts used in homogeneous catalysis.
• Material Science: Employed in the production of liquid crystals, organic semiconductors, and polymers requiring specific aromatic backbones.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form biaryl and aryl amine compounds.
• Chemical Research: A valuable reagent for methodological development in organic chemistry and for creating compound libraries for screening.

Basic Information

Product Name	1-Bromo-3,4-Dichlorobenzene
CAS No.	18282-59-2
Molecular Formula	C6H3BrCl2
Molecular Weight	225.90 g/mol
Synonyms	3,4-Dichlorobromobenzene; 3,4-Dichloro-1-bromobenzene; 4-Bromo-1,2-dichlorobenzene; NSC 87682; Benzene, 1-bromo-3,4-dichloro-
EINECS	Contact for details

Quality Control

Our 1-Bromo-3,4-Dichlorobenzene is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Melting Point	28 - 32 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.