Description

Hydrogen [4-[[4-(Dimethylamino)Phenyl](3,6-Disulfonato-1-Naphthyl)Methylene]Cyclohexa-2,5-Dien-1-Ylidene]Dimethylammonium is a high-purity, water-soluble cyanine dye derivative, valued for its strong near-infrared (NIR) absorption and fluorescence properties. This compound is critical for applications requiring precise optical detection and labeling due to its excellent photostability and functional sulfonate groups that enhance solubility in aqueous matrices. It is primarily sought by manufacturers and researchers in the biotechnology, medical diagnostics, and advanced material science sectors for developing sensitive assays, optical sensors, and functional dyes.

Application

• NIR Fluorescent Labeling Agent: Used as a covalent tag for biomolecules (proteins, antibodies, nucleic acids) in fluorescence immunoassays (FIA) and in situ hybridization (FISH).
• Optical Sensor Development: A key component in the fabrication of chemical sensors and biosensors for detecting pH, metal ions, or specific analytes based on fluorescence quenching or enhancement.
• Laser Dye and Photonic Material: Employed in the formulation of tunable dye lasers and as an active medium in non-linear optical materials due to its specific absorption/emission profile.
• Histological Staining: Serves as a contrast agent in biomedical imaging and histological staining techniques for enhanced tissue visualization under NIR light.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer in cancer research for its ability to generate reactive oxygen species upon light activation.
• Security Ink and Dye Tracer: Utilized in high-security printing and as a fluorescent tracer in industrial fluid dynamics studies.

Basic Information

Product Name	Hydrogen [4-[[4-(Dimethylamino)Phenyl](3,6-Disulphonato-1-Naphthyl)Methylene]Cyclohexa-2,5-Dien-1-Ylidene]Dimethylammonium
CAS No.	18249-12-2
Molecular Formula	C29H27N2O6S2- • H+
Molecular Weight	555.67 g/mol
Synonyms	IR-783; IR 783 dye; NIR-783; 1H-Benz[e]indolium, 2-[2-[2-chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-benz[e]indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-1,3,3-trimethyl-, chloride (common trade name basis); 2-[2-[2-Chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-benz[e]indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-1,3,3-trimethyl-1H-benz[e]indolium chloride; Cyanine dye IR-783; Heptamethine cyanine dye with sulfonate groups; Near-infrared cyanine dye
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with research-grade and potential in-vitro diagnostic (IVD) application standards. Each lot is characterized for critical parameters including identity, purity, and optical performance. Certificates of Analysis (COA) detailing HPLC purity, absorbance/fluorescence maxima, and functional performance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); prolonged exposure to air, moisture, or strong light should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	Dark green to blue-black powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0% (Area %)
λAbs max (in Methanol)	783 nm ± 5 nm
λEm max (in Methanol)	810 nm ± 10 nm
Water Content (KF)	≤ 5.0 %
Residue on Ignition	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.