Description

(3-Methylbutoxy)Trimethylsilane is a specialized organosilicon compound, also known as isoamyloxytrimethylsilane, valued for its role as a versatile silylating agent and synthetic intermediate. Its core value proposition lies in its ability to introduce the trimethylsilyl (TMS) protecting group to alcohols and other nucleophiles, facilitating complex organic syntheses. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity reagents for sensitive reactions.

Application

• Silylating Agent: Used to protect hydroxyl groups in alcohols, phenols, and carboxylic acids during multi-step organic synthesis, particularly in pharmaceutical intermediate manufacturing.
• Precursor for Silicone Derivatives: Serves as a key starting material in the production of modified silicones and silane coupling agents for specialty polymers.
• Surface Modification: Applied in the treatment of silica, glass, and other inorganic surfaces to impart hydrophobicity or alter surface energy for composite materials.
• Reagent in Chromatography: Utilized for derivatization of analytes in Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC-MS) to improve volatility and detection.
• Lithium-Ion Battery Electrolytes: Investigated as a potential electrolyte additive or precursor for forming stable solid-electrolyte interphase (SEI) layers.
• Catalyst and Ligand Synthesis: Employed in the preparation of organometallic catalysts and ligands used in asymmetric synthesis and polymerization reactions.

Basic Information

Product Name	(3-Methylbutoxy)Trimethylsilane
CAS No.	18246-56-5
Molecular Formula	C8H20OSi
Molecular Weight	160.33 g/mol
Synonyms	Isoamyloxytrimethylsilane; Trimethyl(3-methylbutoxy)silane; (Isoamyloxy)trimethylsilane; 3-Methylbutyloxytrimethylsilane; Silane, trimethyl(3-methylbutoxy)-; O-Isoamyl O-Trimethylsilyl Ether; TMS-Isoamyl Ether
EINECS	Contact for details

Quality Control

Our (3-Methylbutoxy)Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR) spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee supply consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Density (at 20°C)	0.78 - 0.82 g/mL
Refractive Index (n20D)	1.405 - 1.415
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.