Description

4-[(S,E)-1-[(S)-1,2-Dihydroxyethyl]-3-(4-Hydroxyphenyl)-2-Propenyl]-1,2-Benzenediol is a complex, stereochemically defined polyphenolic compound of significant interest in advanced organic synthesis and life science research. Its intricate structure, featuring multiple chiral centers and phenolic hydroxyl groups, makes it a valuable chiral building block and a potential precursor for bioactive molecules. This high-purity intermediate is primarily utilized by research institutions and pharmaceutical development laboratories focusing on novel therapeutic agents, natural product synthesis, and specialized chemical biology studies.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of novel drug candidates, particularly those targeting oxidative stress pathways.
• Biochemical Research: Used as a standard or probe in studies investigating antioxidant mechanisms, enzyme interactions, and free radical scavenging activities.
• Natural Product Synthesis: Acts as a key intermediate in the total or semi-synthesis of complex natural products with polyphenolic frameworks.
• Asymmetric Catalysis: Employed as a chiral ligand precursor or a substrate for developing new stereoselective synthetic methodologies.
• Reference Standard: Utilized as a high-purity analytical standard in HPLC, LC-MS, or NMR for method development and compound identification in complex matrices.

Basic Information

Item	Details
Product Name	4-[(S,E)-1-[(S)-1,2-Dihydroxyethyl]-3-(4-Hydroxyphenyl)-2-Propenyl]-1,2-Benzenediol
CAS No.	18194-29-1
Molecular Formula	C₁₇H₁₈O₆
Molecular Weight	318.32 g/mol
Synonyms	(+)-Dihydroquercetin; Taxifolin; (2R,3R)-Dihydroquercetin; (2R,3R)-3,3',4',5,7-Pentahydroxyflavanone; Larixinic acid; Distylin; Contact for additional synonyms
EINECS	Contact for details

Quality Control

Our production of 4-[(S,E)-1-[(S)-1,2-Dihydroxyethyl]-3-(4-Hydroxyphenyl)-2-Propenyl]-1,2-Benzenediol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.