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tert-Butyltrichlorosilane CAS NO 18171-74-9
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CAS No.:18171-74-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
tert-Butyltrichlorosilane is a highly reactive organosilicon compound primarily used as a versatile silylating and protecting agent in organic synthesis. Its value lies in its ability to introduce the bulky tert-butylsilyl group, which provides exceptional steric protection for sensitive functional groups like alcohols and amines during multi-step chemical processes. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing complex molecules.
Application
- Pharmaceutical Intermediate Synthesis: Key protecting group reagent for hydroxyl and amino functions in the production of active pharmaceutical ingredients (APIs).
- Agrochemical Manufacturing: Used in the synthesis of advanced pesticides and herbicides where selective protection is required.
- Surface Modification Agent: Imparts hydrophobic properties to silica, glass, and other inorganic surfaces for specialized coatings.
- Polymer & Silicone Chemistry: Serves as a monomer or cross-linking agent in the development of specialty silicone polymers and resins.
- Laboratory Research & Development: A critical tool in organic synthesis for academic and industrial R&D focused on novel compound libraries.
- Precursor for Silicon-Containing Compounds: Used to synthesize other tert-butyl-substituted silanes and siloxanes with specific functionalities.
Basic Information
| Item | Details |
|---|---|
| Product Name | tert-Butyltrichlorosilane |
| CAS No. | 18171-74-9 |
| Molecular Formula | C4H9Cl3Si |
| Molecular Weight | 191.56 g/mol |
| Synonyms | t-Butyltrichlorosilane; (1,1-Dimethylethyl)trichlorosilane; Trichloro(tert-butyl)silane; tert-Butylsilicon trichloride; TBTCS; tert-C4H9SiCl3; NSC 93766 |
| EINECS | 242-060-5 |
Quality Control
Our tert-Butyltrichlorosilane is manufactured under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat and incompatible materials. Due to its highly volatile and hygroscopic nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended storage temperature: 2-8°C.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Assay (GC) | ≥ 97.0% |
| Density (at 20°C) | 1.16 - 1.18 g/mL |
| Refractive Index (n20D) | 1.450 - 1.455 |
| Chloride Content | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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