Description

(2-Bromoethyl)Trimethylsilane is a versatile organosilicon reagent featuring a reactive bromoethyl group protected by a trimethylsilyl moiety. This compound is a critical building block in organic synthesis, valued for its ability to introduce functionalized silyl groups and serve as a masked ethylene synthon. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing silicon-containing functional groups or as a linker in prodrug design.
• Agrochemical Synthesis: Used in the production of novel pesticides and herbicides where the silyl-protected bromoethyl chain modifies biological activity and stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the development of specialty silicones, silicone-modified polymers, and surface-functionalized materials.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions, Grignard reagent formation, and as a precursor for Peterson olefination and other carbon-carbon bond forming strategies.
• Liquid Crystal & OLED Material Production: Utilized in the synthesis of organosilicon components for electronic display and lighting technologies.
• Protecting Group Strategy: The trimethylsilyl group can act as a temporary protecting group for alcohols or other functionalities during multi-step syntheses.

Basic Information

Product Name	(2-Bromoethyl)Trimethylsilane
CAS No.	18156-67-7
Molecular Formula	C5H13BrSi
Molecular Weight	181.15 g/mol
Synonyms	2-Bromoethyltrimethylsilane; Trimethyl(2-bromoethyl)silane; (2-Bromoethyl)trimethylsilicon; β-Bromoethyltrimethylsilane; BrCH2CH2Si(CH3)3; 2-(Trimethylsilyl)ethyl bromide; Bromo(trimethylsilyl)ethane
EINECS	242-052-9

Quality Control

Our (2-Bromoethyl)Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to minimize moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.445 - 1.455
Density (20°C)	1.15 - 1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.