Description

2-Amino-3-(3,4,5-Trimethoxy-Phenyl)-Propionic Acid is a specialized non-proteinogenic amino acid derivative featuring a trimethoxyphenyl substituent. This compound matters as a key chiral building block and intermediate in advanced organic synthesis, offering a unique structural motif for constructing complex molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptidomimetics & Drug Design: Used as a constrained amino acid analog in the design and synthesis of peptide mimetics to enhance metabolic stability and bioavailability.
• Chemical Biology Research: Employed as a probe or building block in studying enzyme-substrate interactions and protein structure-function relationships.
• Organic Synthesis: Acts as a versatile intermediate for constructing complex natural product analogs and other fine chemicals requiring a phenylalanine-like structure with modified electronic properties.
• Agrochemical Research: Investigated as a potential intermediate in the synthesis of novel crop protection agents and herbicides.

Basic Information

Product Name	2-Amino-3-(3,4,5-Trimethoxy-Phenyl)-Propionic Acid
CAS No.	18111-22-3
Molecular Formula	C₁₂H₁₇NO₅
Molecular Weight	255.27 g/mol
Synonyms	3,4,5-Trimethoxy-DL-phenylalanine; DL-3,4,5-Trimethoxyphenylalanine; 2-Amino-3-(3,4,5-trimethoxyphenyl)propanoic acid; (RS)-2-Amino-3-(3,4,5-trimethoxyphenyl)propionic acid; NSC 163082; 3-(3,4,5-Trimethoxyphenyl)alanine; α-Amino-3,4,5-trimethoxybenzenepropanoic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-3-(3,4,5-Trimethoxy-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.