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(2-Naphtyloxy)Trimethylsilane CAS NO 18081-08-8


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CAS No.:18081-08-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2-Naphtyloxy)Trimethylsilane is a specialized organosilicon compound featuring a naphthyloxy functional group protected by a trimethylsilyl moiety. This structure makes it a valuable reagent and intermediate in advanced organic synthesis, particularly for introducing the 2-naphthyloxy group under mild conditions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing complex molecules, liquid crystals, or functional polymers.

Application

  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates where the naphthalene scaffold is required.
  • Agrochemical Synthesis: Serves as a key building block for creating advanced herbicides, fungicides, and plant growth regulators.
  • Material Science: Employed in the production of specialty polymers, liquid crystals, and organic electronic materials for its aromatic and silyl ether properties.
  • Organic Synthesis Reagent: Acts as a protected form of 2-naphthol, facilitating nucleophilic substitution reactions in sensitive synthetic pathways.
  • Cross-Coupling Reactions: A potential substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing biaryl systems.
  • Research & Development: A crucial tool for medicinal chemistry and process chemistry research in academic and industrial laboratories.

Basic Information

Product Name (2-Naphtyloxy)Trimethylsilane
CAS No. 18081-08-8
Molecular Formula C₁₃H₁₆OSi
Molecular Weight 216.35 g/mol
Synonyms 2-(Trimethylsilyloxy)naphthalene; Trimethyl(2-naphthyloxy)silane; 2-Naphthol trimethylsilyl ether; O-Trimethylsilyl-2-naphthol; 2-Naphthyloxytrimethylsilane; 2-(Trimethylsiloxy)naphthalene; Naphthalen-2-yloxy-trimethylsilane; TMS-ONap
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Quality Control

Our (2-Naphtyloxy)Trimethylsilane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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