Description

1-Phenyl-1H-Imidazole-4-Carboxylic Acid is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its functionalized imidazole scaffold, which serves as a critical precursor for the development of pharmaceuticals, agrochemicals, and specialty materials. This compound is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Development: Used in the research and production of novel fungicides, herbicides, and plant growth regulators due to its bioactive imidazole core.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic electronic materials, polymers, and dyes where the imidazole moiety imparts specific electronic properties.
• Bioconjugation Chemistry: The carboxylic acid group allows for coupling reactions, making it useful in probe and linker molecule development for biochemical applications.

Basic Information

Product Name	1-Phenyl-1H-Imidazole-4-Carboxylic Acid
CAS No.	18075-64-4
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	1-Phenyl-1H-imidazole-4-carboxylic acid; 4-Imidazolecarboxylic acid, 1-phenyl-; 1-Phenylimidazole-4-carboxylic acid; 1-Phenyl-4-imidazolecarboxylic acid; NSC 403697; 1-Phenyl-1H-imidazole-4-carboxylate; 4-Carboxy-1-phenylimidazole; 1-Phenyl-4-carboxyimidazole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, impurities, and physical properties are available upon request. We adhere to strict quality management protocols suitable for cGMP and ISO environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.