Description

6-Amino-1-Ethyl-2-Methyl-5-(Trifluoromethyl)-1H-Benzimidazole is a specialized benzimidazole derivative, a high-value chemical intermediate prized for its unique trifluoromethyl-substituted aromatic structure. This compound matters for its role in synthesizing advanced molecules, particularly in the pharmaceutical sector where the trifluoromethyl group is a key pharmacophore known to enhance metabolic stability and bioavailability. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material industries for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the benzimidazole core and fluorine atoms contribute to biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in OLED displays and lighting due to its rigid, conjugated structure.
• Ligand for Catalysis: Can be utilized to create complex ligands for transition metal catalysts used in fine chemical synthesis.
• Fluorescent Probe Development: Acts as a core structure for designing sensitive fluorescent dyes and probes used in biochemical assays and diagnostics.
• Academic & Industrial R&D: Employed in chemical research to explore new reactions and properties of fluorinated heterocyclic compounds.

Basic Information

Product Name	6-Amino-1-Ethyl-2-Methyl-5-(Trifluoromethyl)-1H-Benzimidazole
CAS No.	18018-34-3
Molecular Formula	C11H12F3N3
Molecular Weight	243.23 g/mol
Synonyms	5-(Trifluoromethyl)-1-ethyl-2-methyl-1H-benzimidazol-6-amine; 1-Ethyl-2-methyl-5-(trifluoromethyl)-1H-benzimidazol-6-amine; 6-Amino-1-ethyl-2-methyl-5-trifluoromethylbenzimidazole; 18018-34-3; 5-Trifluoromethyl-1-ethyl-2-methyl-6-aminobenzimidazole; 1H-Benzimidazole, 6-amino-1-ethyl-2-methyl-5-(trifluoromethyl)-; 6-Amino-1-ethyl-2-methyl-5-(trifluoromethyl)benzimidazole
EINECS	Contact for details

Quality Control

Our 6-Amino-1-Ethyl-2-Methyl-5-(Trifluoromethyl)-1H-Benzimidazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.