Description

n-6,9-Bis(Trimethylsilyl)Adenine is a silylated derivative of the nucleobase adenine, designed to enhance solubility and stability in organic synthesis. This compound is a crucial protected intermediate for the controlled functionalization of adenine, enabling precise chemical modifications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of nucleoside analogs, active pharmaceutical ingredients (APIs), and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Agrochemical Research: Used in creating novel plant growth regulators or pesticides based on modified nucleobase structures.
• Oligonucleotide Synthesis: Serves as a protected monomer for the solid-phase synthesis of modified DNA/RNA strands in diagnostic and therapeutic applications.
• Chemical Biology Probes: Enables the site-specific labeling or functionalization of adenine-containing biomolecules for mechanistic studies.
• Material Science: Precursor for creating functionalized polymers or surfaces with nucleobase recognition properties.
• Academic & Industrial R&D: Fundamental reagent for exploring new reaction pathways in heterocyclic and organosilicon chemistry.

Basic Information

Product Name	n-6,9-Bis(Trimethylsilyl)Adenine
CAS No.	17995-04-9
Molecular Formula	C11H21N5Si2
Molecular Weight	267.49 g/mol
Synonyms	6,9-Bis(trimethylsilyl)adenine; 6,9-Bis(trimethylsilyl)-9H-purine-6-amine; Adenine, 6,9-bis(trimethylsilyl)-; N6,N9-Bis(trimethylsilyl)adenine; 6-Amino-9-(trimethylsilyl)-9H-purine-9-trimethylsilane; BTSA; 6,9-BTMS-Ade
EINECS	Contact for details

Quality Control

Our n-6,9-Bis(Trimethylsilyl)Adenine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for research and process chemistry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.