Description

3-Bromo-1,8-Naphthyridine is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its ability to act as a key precursor for constructing complex molecular architectures, particularly in the development of pharmaceuticals and functional materials. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds and ligands.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active molecules containing the 1,8-naphthyridine scaffold.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the bromine atom allows for further functionalization.
• Material Science Precursor: Serves as a building block for creating organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials due to its rigid, planar structure.
• Ligand Synthesis: Employed in the preparation of nitrogen-containing ligands for catalysis and coordination chemistry.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on heterocyclic chemistry and medicinal chemistry.

Basic Information

Product Name	3-Bromo-1,8-Naphthyridine
CAS No.	17965-78-5
Molecular Formula	C8H5BrN2
Molecular Weight	209.04 g/mol
Synonyms	3-Bromo-1,8-naphthyridine; 1,8-Naphthyridine, 3-bromo-; 3-Bromonaphthyridine; 3-Bromo[1,8]naphthyridine; Bromo-1,8-naphthyridine; 3-Br-1,8-Naph
EINECS	Contact for details

Quality Control

Our 3-Bromo-1,8-Naphthyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.