Description

Bis(Trimethylsilyl)Hypoxathine is a specialized organosilicon compound, a silylated derivative of hypoxanthine, widely recognized by its CAS number 17962-89-9. This reagent is valued for its role as a versatile protecting group and intermediate in sophisticated organic synthesis, particularly in nucleoside and nucleotide chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require high-purity building blocks for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key protected intermediate in the synthesis of nucleoside analogs and antiviral/anticancer prodrugs.
• Oligonucleotide Synthesis: Used in the preparation of modified nucleic acids for research, diagnostics, and therapeutic applications.
• Protecting Group Chemistry: Serves as a trimethylsilyl (TMS) protecting agent for the hydroxyl groups of heterocyclic compounds, enabling selective reactions.
• Agrochemical Research: Employed in the development of novel pesticides and plant growth regulators that utilize modified nucleobase structures.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways in academic and industrial R&D laboratories.
• Material Science: Potential precursor for silicon-containing organic frameworks or specialty polymers.

Basic Information

Product Name	Bis(Trimethylsilyl)Hypoxathine
CAS No.	17962-89-9
Molecular Formula	C₁₂H₂₄N₄OSi₂
Molecular Weight	284.51 g/mol
Synonyms	1,9-Bis(trimethylsilyl)hypoxanthine; 6-Oxo-1,9-bis(trimethylsilyl)-1,9-dihydropurine; N,O-Bis(trimethylsilyl)hypoxanthine; Hypoxanthine, 1,9-bis(trimethylsilyl)-; BTH; TMS-Hypoxanthine
EINECS	Contact for details

Quality Control

Our Bis(Trimethylsilyl)Hypoxathine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C. Keep the container in a cool, dry, and well-ventilated area, away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.