Description

4-Bromocinnamic Acid is a versatile halogenated aromatic building block of significant importance in synthetic organic chemistry. Its core value lies in its reactive carboxylic acid and vinyl bromide functionalities, enabling its use as a key precursor for cross-coupling reactions and the synthesis of complex molecular frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting inflammation and CNS disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the bromine atom facilitates further functionalization.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating brominated aromatic cores essential in the manufacture of electronic display materials.
• Cross-Coupling Reactions: Acts as a competent substrate in Heck, Suzuki, and Stille coupling reactions to form extended conjugated systems.
• Polymer Modification: Incorporated into polymer backbones to impart specific properties like flame retardancy or altered refractive indices.
• Chemical Research & Development: A standard reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating specialized chemical libraries.

Basic Information

Product Name	4-Bromocinnamic Acid
CAS No.	17916-60-8
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	(E)-3-(4-Bromophenyl)acrylic Acid; trans-4-Bromocinnamic Acid; 4-Bromo-trans-cinnamic Acid; 3-(4-Bromophenyl)-2-propenoic Acid; p-Bromocinnamic Acid; (E)-3-(4-Bromophenyl)-2-propenoic Acid; 2-Propenoic acid, 3-(4-bromophenyl)-, (E)-; 4-Bromobenzeneacrylic Acid
EINECS	Contact for details

Quality Control

Our 4-Bromocinnamic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	250°C - 255°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.