Description

Trimethyl-(4-Methylphenoxy)Silane is a specialized organosilicon compound, also known as p-Cresoxytrimethylsilane, valued for its role as a versatile silylating agent and synthetic intermediate. Its primary commercial significance lies in its ability to introduce the trimethylsilyl (TMS) protecting group onto phenolic hydroxyl groups, enabling complex organic syntheses. This product is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and advanced materials sectors, where precise chemical modification and protection strategies are required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) where protection of phenolic -OH groups is necessary.
• Agrochemical Synthesis: Serves as a key building block in the production of herbicides, fungicides, and other crop protection agents.
• Silicon-Based Polymer Modification: Acts as a coupling agent or end-capper in the production and modification of silicones and siloxane polymers.
• Surface Treatment Agent: Utilized to impart hydrophobic properties to glass, silica, or other inorganic surfaces.
• Analytical Chemistry Reagent: Employed in gas chromatography (GC) and mass spectrometry (MS) for derivatization of phenolic compounds to improve volatility and detection.
• Organic Synthesis Building Block: Facilitates various reactions, including nucleophilic substitutions and cross-coupling reactions, in fine chemical production.

Basic Information

Product Name	Trimethyl-(4-Methylphenoxy)Silane
CAS No.	17902-32-8
Molecular Formula	C10H16OSi
Molecular Weight	180.32 g/mol
Synonyms	p-Cresoxytrimethylsilane; (4-Methylphenoxy)trimethylsilane; Trimethyl(p-tolyloxy)silane; Silane, trimethyl(4-methylphenoxy)-; 4-Methylphenoxytrimethylsilane; p-Tolyloxytrimethylsilane; TMS-p-cresyl ether; Trimethylsilane, (p-methylphenoxy)-
EINECS	Contact for details

Quality Control

Our Trimethyl-(4-Methylphenoxy)Silane is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is easily oxidized; for long-term storage, it is recommended to keep under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.2%
Refractive Index (n20D)	1.480 - 1.490
Density (20°C)	0.92 - 0.96 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.