Description

3-(Trimethylsilyl)Phenol is a versatile organosilicon intermediate featuring a phenolic hydroxyl group protected by a trimethylsilyl moiety. This compound is valued for its role in organic synthesis, where it serves as a protected phenol building block, enabling selective reactions in the creation of complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) where a protected phenol group is required for selective coupling or functionalization.
• Agrochemical Synthesis: Serves as a key building block in the production of herbicides, fungicides, and other crop protection agents.
• Polymer & Material Science: Employed as a monomer or modifier in the development of silicone-based polymers, resins, and specialty coatings to impart specific thermal or surface properties.
• Organic Synthesis Reagent: Acts as a versatile reagent in cross-coupling reactions (e.g., Suzuki, Heck) and as a precursor for other silylated aromatic compounds.
• Liquid Crystal & OLED Materials: Utilized in the synthesis of advanced electronic materials for displays and lighting due to its ability to modify molecular structure and properties.
• Flavor & Fragrance Industry: Can be used as an intermediate in the synthesis of certain aromatic compounds for specialty fragrances.

Basic Information

Product Name	3-(Trimethylsilyl)Phenol
CAS No.	17881-95-7
Molecular Formula	C9H14OSi
Molecular Weight	166.29 g/mol
Synonyms	3-Hydroxyphenyltrimethylsilane; m-(Trimethylsilyl)phenol; Phenol, 3-(trimethylsilyl)-; Trimethyl(3-hydroxyphenyl)silane; 3-TMS-Phenol; m-TMS-Phenol; 3-(Trimethylsilyl)benzenol
EINECS	Contact for details

Quality Control

Our 3-(Trimethylsilyl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.