Description

1-Bromo-3-Trimethylsilylbenzene is a high-purity organosilicon intermediate featuring both a bromo and a trimethylsilyl functional group on the benzene ring. This unique bifunctional structure makes it a versatile and valuable building block for advanced organic synthesis, particularly in the development of complex molecules. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for constructing novel compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring silicon-containing bioactive molecules or protected aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the silyl group can act as a protecting group or be incorporated into the final product.
• Material Science & OLED Development: Serves as a building block for creating organic semiconductors, liquid crystals, and light-emitting materials for electronic displays.
• Cross-Coupling Reactions: The bromine atom is an excellent site for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille), enabling the introduction of complex substituents.
• Ligand & Catalyst Preparation: Utilized in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Organic Synthesis & Protecting Group Strategy: The trimethylsilyl group can be used to protect sensitive sites or later be transformed into other functional groups like hydroxyls.

Basic Information

Product Name	1-Bromo-3-Trimethylsilylbenzene
CAS No.	17878-47-6
Molecular Formula	C9H13BrSi
Molecular Weight	229.19 g/mol
Synonyms	3-Bromophenyltrimethylsilane; (3-Bromophenyl)trimethylsilane; m-Bromophenyltrimethylsilane; Trimethyl(3-bromophenyl)silane; 3-Bromo-1-(trimethylsilyl)benzene; Benzene, 1-bromo-3-(trimethylsilyl)-; TMS-3-Bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Trimethylsilylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.