Description

1,3-Bis-Trimethylsilanyl-Imidazolidin-2-One is a specialized organosilicon compound used as a versatile silylating agent and protecting group in advanced organic synthesis. Its primary value lies in its ability to efficiently protect sensitive functional groups, particularly amines and alcohols, under mild conditions, facilitating complex multi-step reactions. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require reliable and high-yielding synthetic methodologies.

Application

• As a silylating agent for the protection of amines, alcohols, and other nucleophiles in complex molecule synthesis.
• Key intermediate in the production of active pharmaceutical ingredients (APIs) and fine chemicals requiring sensitive functional group manipulation.
• Used in peptide synthesis to protect amino groups, preventing unwanted side reactions.
• Facilitates nucleoside and nucleotide chemistry for the development of antiviral and anticancer drugs.
• Employed in agrochemical research for the synthesis of novel herbicides and pesticides.
• Useful in material science for surface modification and the synthesis of silicon-containing polymers.
• Acts as a reagent in analytical chemistry for derivatization to improve chromatographic analysis of polar compounds.

Basic Information

Product Name	1,3-Bis-Trimethylsilanyl-Imidazolidin-2-One
CAS No.	17877-19-9
Molecular Formula	C9H22N2O1Si2
Molecular Weight	230.45 g/mol
Synonyms	1,3-Bis(trimethylsilyl)imidazolidin-2-one; 1,3-Bis(trimethylsilyl)-2-imidazolidinone; 2-Imidazolidinone, 1,3-bis(trimethylsilyl)-; BTSI; N,O-Bis(trimethylsilyl)imidazolidinone; 1,3-Bis-O-trimethylsilylimidazolidin-2-one; 1,3-Di(trimethylsilyl)imidazolidin-2-one
EINECS	Contact for details

Quality Control

Our 1,3-Bis-Trimethylsilanyl-Imidazolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.