Description

Piperidine, 1-((Trimethylsilyl)Methyl)- is a specialized organosilicon derivative of piperidine, featuring a reactive trimethylsilylmethyl group. This compound is valued for its dual functionality, serving as a versatile building block in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring functionalized piperidine scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the silylated group can modulate biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands in transition metal catalysis and organocatalysis.
• Material Science: Building block for silicon-modified polymers and advanced organic materials, influencing thermal and mechanical properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution reactions, carbanion chemistry, and as a protecting group strategy due to the reactivity of the silylmethyl unit.

Basic Information

Product Name	Piperidine, 1-((Trimethylsilyl)Methyl)-
CAS No.	17877-17-7
Molecular Formula	C9H21NSi
Molecular Weight	171.36 g/mol
Synonyms	1-((Trimethylsilyl)methyl)piperidine; (Trimethylsilylmethyl)piperidine; N-((Trimethylsilyl)methyl)piperidine; N-(Trimethylsilylmethyl)piperidine; Piperidine, 1-(trimethylsilylmethyl)-; 1-(Trimethylsilylmethyl)piperidine; N-(Trimethylsilyl)methylpiperidine
EINECS	Contact for details

Quality Control

Our Piperidine, 1-((Trimethylsilyl)Methyl)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.