Description

3-(Trimethylsilyl)Anisole is a versatile organosilicon compound featuring a trimethylsilyl group attached to an anisole ring, making it a valuable reagent in advanced organic synthesis. Its primary value lies in its dual functionality, serving as both a robust protecting group for phenols and a versatile intermediate for constructing complex molecular architectures. This chemical is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors who require high-purity intermediates for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly where phenol protection is required.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that require silicon-containing motifs for enhanced activity or stability.
• Material Science Precursor: Serves as a monomer or modifying agent in the development of specialty silicones and silicon-based polymers.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a silylating agent in laboratory-scale and pilot-plant syntheses.
• Liquid Crystal & OLED Material Research: Acts as an intermediate in the creation of silicon-based compounds for electronic display applications.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing novel aromatic compounds with modified scent profiles.

Basic Information

Product Name	3-(Trimethylsilyl)Anisole
CAS No.	17876-90-3
Molecular Formula	C10H16OSi
Molecular Weight	180.32 g/mol
Synonyms	3-Methoxy(trimethylsilyl)benzene; m-(Trimethylsilyl)anisole; Anisole, 3-(trimethylsilyl)-; 1-Methoxy-3-(trimethylsilyl)benzene; Benzene, 1-methoxy-3-(trimethylsilyl)-; Trimethyl(3-methoxyphenyl)silane; 3-Trimethylsilylanisole
EINECS	Contact for details

Quality Control

Our 3-(Trimethylsilyl)Anisole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to verify identity, potency, and impurity profiles. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.