Description

Adamantane-1-Carbohydrazide is a high-purity, functionalized adamantane derivative characterized by its rigid, cage-like hydrocarbon structure and a reactive carbohydrazide moiety. This unique combination of structural stability and functional group reactivity makes it a valuable advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active compounds and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and antiviral medications, leveraging the lipophilic adamantane core for enhanced blood-brain barrier penetration.
• Ligand and Chelating Agent Synthesis: The carbohydrazide group acts as an effective ligand for metal ions, useful in creating catalysts or metal-organic frameworks (MOFs) for specialized chemical processes.
• Polymer Modification: Employed as a functional monomer or cross-linking agent to introduce rigid, thermally stable adamantane units into polymer backbones, improving material properties.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the stable adamantane structure can contribute to prolonged environmental stability and efficacy.
• Organic Synthesis Building Block: A versatile reagent for constructing complex molecular architectures via condensation reactions, hydrazone formation, and other transformations involving the hydrazide functionality.
• Material Science Research: Investigated for creating novel organic semiconductors, liquid crystals, or coatings due to its defined three-dimensional geometry and potential for derivatization.

Basic Information

Product Name	Adamantane-1-Carbohydrazide
CAS No.	17846-15-0
Molecular Formula	C11H18N2O
Molecular Weight	194.28 g/mol
Synonyms	1-Adamantanecarbohydrazide; 1-Adamantylcarbohydrazide; Adamantane-1-carboxylic acid hydrazide; Adamantane-1-carbohydrazide; 1-Carbohydrazidoadamantane; Tricyclo[3.3.1.13,7]decane-1-carbohydrazide; 1-Adamantoylhydrazine; Adamantyl-1-carbohydrazide
EINECS	Contact for details

Quality Control

Our Adamantane-1-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can support development and production needs across various purity grades, from research (≥97%) to pharmaceutical intermediate (≥99%) specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.