Description

6-Chlorotryptophan is a halogenated derivative of the essential amino acid tryptophan, serving as a critical chiral building block in advanced organic synthesis. This compound is valued for its role in introducing the indole scaffold with a chlorine substituent, enabling the development of novel molecules with modified biological activity and physicochemical properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), peptidomimetics, and complex bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Peptide Chemistry: Used for the site-specific incorporation of a halogenated tryptophan analog into synthetic peptides and peptidomimetics to study structure-activity relationships.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and as a probe in metabolic pathway analysis.
• Agrochemical Development: Serves as a building block for synthesizing novel compounds with potential herbicidal or insecticidal activity.
• Material Science: Potential monomer for creating specialized polymers and advanced materials with unique electronic or photophysical properties.

Basic Information

Product Name	6-Chlorotryptophan
CAS No.	17808-35-4
Molecular Formula	C11H11ClN2O2
Molecular Weight	238.67 g/mol
Synonyms	(S)-2-Amino-3-(6-chloro-1H-indol-3-yl)propanoic acid; 6-Chloro-L-tryptophan; L-6-Chlorotryptophan; 6-Cl-Trp; 6-Chloroindole-3-alanine; 6-Chlorotryptophane; 6-Chloro-1H-indole-3-alanine; 6-Chlorotryptophan, L-
EINECS	Contact for details

Quality Control

Our 6-Chlorotryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.