Description

Ethyl 3-(Trimethylsilyl)Propionate is a versatile organosilicon compound that serves as a valuable building block and protecting group reagent in advanced organic synthesis. Its unique structure, featuring both a silyl group and an ester functionality, makes it a critical intermediate for modifying molecular properties and enabling complex chemical transformations. This high-purity reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing silicon-containing moieties or as a protected carboxylic acid equivalent.
• Agrochemical Synthesis: Serves as a key precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Employed as a monomer or modifying agent for creating silicone-modified polymers, resins, and coatings with tailored properties like flexibility, thermal stability, or surface characteristics.
• Organic Synthesis Reagent: Functions as a versatile reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction and other carbon-carbon bond-forming processes.
• Flavor & Fragrance Industry: Acts as an intermediate in the production of specific silicon-based aroma chemicals.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating complex molecular architectures.

Basic Information

Product Name	Ethyl 3-(Trimethylsilyl)Propionate
CAS No.	17728-88-0
Molecular Formula	C8H18O2Si
Molecular Weight	174.31 g/mol
Synonyms	3-(Trimethylsilyl)propionic Acid Ethyl Ester; Ethyl 3-(Trimethylsilyl)propanoate; Ethyl β-(Trimethylsilyl)propionate; TMS-Propionate Ethyl Ester; (3-Ethoxy-3-oxopropyl)trimethylsilane; NSC 163045; Trimethylsilylpropionic Acid Ethyl Ester; TESPP
EINECS	241-734-5

Quality Control

Our Ethyl 3-(Trimethylsilyl)Propionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring consistent quality and traceability for demanding industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C/59-77°F) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.415 - 1.425
Density (g/mL at 25°C)	0.88 - 0.92

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.