Description

2-Chloro-1-Buten-3-Yne (CAS NO 17712-36-6) is a highly reactive halogenated alkyne building block essential for advanced organic synthesis. Its unique structure, featuring both a chlorine atom and a terminal alkyne, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries to introduce functionalized acetylene units into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing acetylene-linked pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that require halogenated alkyne components.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers and specialty resins with tailored properties.
• Organic Synthesis Building Block: Employed in Sonogashira coupling, click chemistry, and other metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new reaction methodologies and complex molecule construction.

Basic Information

Product Name	2-Chloro-1-Buten-3-Yne
CAS No.	17712-36-6
Molecular Formula	C₄H₃Cl
Molecular Weight	86.52 g/mol
Synonyms	2-Chlorobuten-3-yne; 1-Chloro-2-butyne-3-ene; 2-Chloro-3-buten-1-yne; 3-Buten-1-yne, 2-chloro-; Chlorovinylacetylene; 2-Chlorovinylacetylene; 1-Chloro-3-buten-1-yne
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-Buten-3-Yne is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical specifications. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and reactive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, well-ventilated place. Recommended storage temperature is 2-8°C. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.