Description

5-Benzyloxy-2-Bromotoluene is a high-purity brominated aromatic ether, a key synthetic intermediate in advanced organic chemistry. This compound is valued for its versatile reactivity, particularly in cross-coupling reactions and as a building block for complex molecular architectures. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing complex diaryl ether or biphenyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where its bromine atom facilitates further functionalization.
• Material Science Research: Acts as a monomer or building block in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	5-Benzyloxy-2-Bromotoluene
CAS No.	17671-75-9
Molecular Formula	C₁₄H₁₃BrO
Molecular Weight	277.16 g/mol
Synonyms	2-Bromo-5-(benzyloxy)toluene; 1-Bromo-4-(benzyloxy)-2-methylbenzene; 4-Benzyloxy-2-bromotoluene; Toluene, 5-(benzyloxy)-2-bromo-; 2-Methyl-4-(benzyloxy)bromobenzene; 5-Benzyloxy-2-bromotoluene; 2-Bromo-5-phenylmethoxytoluene
EINECS	Contact for details

Quality Control

Our 5-Benzyloxy-2-Bromotoluene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.