Description

Z-D-Phg-Oh CAS NO 17609-52-8 is a high-purity, protected amino acid derivative, specifically the Z-protected (benzyloxycarbonyl) form of D-phenylglycine. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering precise stereochemical control. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs), peptides, and specialized catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of β-lactam antibiotics, such as certain cephalosporins and penicillins.
• Peptide Synthesis: Used as a protected D-phenylglycine residue in solid-phase and solution-phase peptide synthesis to construct peptides with specific biological activities.
• Catalyst & Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Biochemical Research: Employed in proteomics and enzymology studies as a substrate analog or inhibitor.
• Fine Chemical Synthesis: A versatile intermediate for creating complex molecules in agrochemicals and specialty materials.

Basic Information

Product Name	Z-D-Phg-Oh
CAS No.	17609-52-8
Molecular Formula	C16H15NO4
Molecular Weight	285.29 g/mol
Synonyms	N-Carbobenzyloxy-D-phenylglycine; (R)-2-((Benzyloxy)carbonylamino)-2-phenylacetic acid; Z-D-α-Phenylglycine; Cbz-D-Phenylglycine; N-Cbz-D-phenylglycine; (R)-2-(Benzyloxycarbonylamino)-2-phenylacetic acid; D-2-Phenyl-2-[(phenylmethoxy)carbonylamino]acetic acid; Benzyl (R)-2-carboxy-2-phenylcarbamate
EINECS	Contact for details

Quality Control

Our Z-D-Phg-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing purity, specific rotation, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Specific Rotation	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.