Description

Ethyl L-Valinate Hydrochloride is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the controlled introduction of the valine side chain in complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the production of peptides, active pharmaceutical ingredients (APIs), and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs, protease inhibitors, and other therapeutic agents.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate L-valine residues with an ethyl ester protecting group.
• Bioconjugation & Linker Chemistry: Employed in the development of antibody-drug conjugates (ADCs) and other targeted delivery systems.
• Asymmetric Synthesis: Acts as a starting material or auxiliary in the preparation of enantiomerically pure compounds for agrochemicals and specialty chemicals.
• Biochemical Research: Utilized in academic and industrial research for studying enzyme mechanisms, protein folding, and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	Ethyl L-Valinate Hydrochloride
CAS No.	17609-47-1
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	L-Valine ethyl ester hydrochloride; (S)-2-Amino-3-methylbutanoic acid ethyl ester hydrochloride; Ethyl L-valinate HCl; Valine ethyl ester hydrochloride; H-Val-OEt·HCl; Ethyl (2S)-2-amino-3-methylbutanoate hydrochloride; Ethyl L-2-amino-3-methylbutyrate hydrochloride; L-Valine ethyl ester HCl
EINECS	Contact for details

Quality Control

Our Ethyl L-Valinate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.