Description

2-Iodonaphthalene-1-Carboxylic Acid is a high-purity iodinated naphthalene derivative, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in the synthesis of pharmaceuticals and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds and facilitating cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders and anti-cancer agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, leveraging its halogenated aromatic structure.
• Material Science Precursor: Serves as a monomer or precursor in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions, such as Suzuki-Miyaura and Sonogashira couplings, for carbon-carbon bond formation.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Dye and Pigment Research: Intermediate in the synthesis of complex organic dyes and pigments due to the naphthalene core.
• Academic and Contract Research: A valuable reagent for methodological studies and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	2-Iodonaphthalene-1-Carboxylic Acid
CAS No.	17542-06-2
Molecular Formula	C11H7IO2
Molecular Weight	298.08 g/mol
Synonyms	1-Carboxy-2-iodonaphthalene; 2-Iodo-1-naphthalenecarboxylic acid; 2-Iodo-1-naphthoic acid; 1-Naphthalenecarboxylic acid, 2-iodo-; 2-Iodonaphthalene-1-carboxylic acid; 2-Iodo-1-naphthalenecarboxylic acid; 2-Iodonaphthoic acid; 2-Iodo-1-naphthoic acid
EINECS	Contact for details

Quality Control

Our 2-Iodonaphthalene-1-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.