Description

n-Propyldimethylchlorosilane is a highly reactive organosilicon compound, specifically a chlorosilane, widely used as a versatile silylating agent and synthetic intermediate. Its core value proposition lies in its ability to introduce the n-propyldimethylsilyl protecting group, offering a critical tool for modifying molecular properties and enhancing stability in sensitive chemical processes. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable reagents for synthesis, derivatization, and surface functionalization.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key protecting group reagent for hydroxyl and other functional groups during the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Production: Employed in the manufacture of pesticides and herbicides where silylation improves compound stability or alters bioavailability.
• Surface Modification Agent: Functionalizes silica, glass, and other inorganic surfaces to create hydrophobic coatings or to attach specific organic moieties.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty silicones and silicon-based polymers.
• Analytical Chemistry: Utilized for derivatizing polar compounds in Gas Chromatography (GC) and Mass Spectrometry (MS) to improve volatility and detection.
• Fine Chemical Synthesis: Serves as a versatile building block in organic synthesis for constructing complex molecular architectures in R&D laboratories.

Basic Information

Product Name	n-Propyldimethylchlorosilane
CAS No.	17477-29-1
Molecular Formula	C5H13ClSi
Molecular Weight	136.70 g/mol
Synonyms	Chlorodimethylpropylsilane; Dimethylpropylchlorosilane; Propyl(dimethyl)chlorosilane; 1-Propyldimethylchlorosilane; Dimethyl(propyl)silyl chloride; (Dimethylpropylsilyl)chloride; n-Propylchlorodimethylsilane; DMPrClSi
EINECS	241-488-3

Quality Control

Our n-Propyldimethylchlorosilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with internal quality standards and customer-specific requirements for research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this material must be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as water, alcohols, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Density (at 25°C)	0.88 - 0.90 g/mL
Refractive Index (n20/D)	1.418 - 1.422
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.