Description

Lithium Tri-tert-Butoxyaluminum Hydride is a highly selective and versatile reducing agent, known for its mild reactivity and excellent solubility in organic solvents. This compound is particularly valued for its ability to perform chemoselective reductions of carbonyl groups, such as converting acid chlorides to aldehydes, without over-reduction. It is an essential reagent for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise control over synthetic pathways.

Application

• Selective Reduction of Acid Chlorides to Aldehydes: A key application where it acts as a superior alternative to lithium aluminum hydride (LiAlH4), preventing further reduction to the alcohol.
• Pharmaceutical Intermediate Synthesis: Used in the production of complex drug molecules where chemoselectivity is critical to avoid side reactions and protect sensitive functional groups.
• Fine Chemical and Agrochemical Manufacturing: Employed in the synthesis of specialty chemicals, flavors, fragrances, and active ingredients for crop protection.
• Polymer Chemistry: Acts as a catalyst or initiator in specific polymerization reactions and in the modification of polymer precursors.
• Academic and Industrial R&D: A staple reagent in laboratory-scale research for developing new synthetic methodologies and exploring novel chemical transformations.
• Steroid and Natural Product Synthesis: Useful in the selective reduction of ketones or other carbonyl functionalities within complex, polyfunctional molecules.

Basic Information

Product Name	Lithium Tri-tert-Butoxyaluminum Hydride
CAS No.	17476-04-9
Molecular Formula	C12H28AlLiO3
Molecular Weight	254.28 g/mol
Synonyms	Lithium Tri-tert-butoxyaluminum Hydride; Lithium Tri-tert-butoxyaluminohydride; Lithium Tri-tert-butyloxyaluminum Hydride; Lithium Tri-tert-butoxyaluminumhydride; Lithium Hydridotri(tert-butoxy)aluminate; Lithium Tri(tert-butoxy)aluminum Hydride; LTBAL-H; LiAlH(O-t-Bu)3
EINECS	Contact for details

Quality Control

Our Lithium Tri-tert-Butoxyaluminum Hydride is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA details key parameters including assay (by titration), identity confirmation (IR), and impurity profiles, ensuring the material meets the rigorous standards required for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Due to its properties of being easily oxidized (store under inert atmosphere), hygroscopic (moisture-sensitive), and highly volatile, it is recommended to store at 2-8°C for long-term stability. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to reference spectrum
Assay (Titration)	≥ 95.0%
Solubility (in THF or Toluene)	Clear, colorless solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.