Description

(+)-3,4,5-Trihydroxybenzoic Acid (2S,3R)-3,4-Dihydro-7-Hydroxy-2-(3,4,5-Trihydroxyphenyl)-2H-1-Benzopyran-3-Yl Ester is a high-purity, complex polyphenolic ester compound of significant interest in advanced research and development. This compound is valued for its specific stereochemistry and potential bioactive properties derived from its gallic acid and flavan-3-ol structural motifs. It serves as a critical reference standard and key intermediate for pharmaceutical, nutraceutical, and life science applications requiring precise molecular characterization.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of complex natural product-derived APIs in analytical laboratories.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies related to polyphenol metabolism, antioxidant pathways, and cellular signaling.
• Nutraceutical Development: Serves as a high-grade ingredient or marker compound for advanced dietary supplements targeting oxidative stress.
• Cosmeceutical Actives: Incorporated into premium skincare formulations for its potential antioxidant and skin-protective properties.
• Organic Synthesis Intermediate: Provides a chiral, multifunctional building block for the synthesis of more complex therapeutic candidates and specialty chemicals.
• Quality Control & Method Development: Essential for developing and validating analytical methods (HPLC, LC-MS) in compliance with GLP and GMP guidelines.

Basic Information

Product Name	(+)-3,4,5-Trihydroxybenzoic Acid (2S,3R)-3,4-Dihydro-7-Hydroxy-2-(3,4,5-Trihydroxyphenyl)-2H-1-Benzopyran-3-Yl Ester
CAS No.	17445-91-9
Molecular Formula	C22H18O11
Molecular Weight	458.37 g/mol
Synonyms	Gallocatechin Gallate; GCG; (-)-Gallocatechin 3-Gallate; (2S,3R)-3,4-Dihydro-7-hydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate; (+)-Gallocatechin Gallate; Epigallocatechin Gallate isomer; Flavan-3-ol gallate; Tea Catechin Ester
EINECS	Contact for details

Quality Control

Every batch of our (+)-3,4,5-Trihydroxybenzoic Acid (2S,3R)-3,4-Dihydro-7-Hydroxy-2-(3,4,5-Trihydroxyphenyl)-2H-1-Benzopyran-3-Yl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, chiral purity confirmation, and identity verification (IR, MS) to ensure it meets the exacting standards for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, and custom purity grades or specific impurity profiles can be accommodated upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% (2S,3R)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.