Description

Swertiamarine is a naturally occurring secoiridoid glycoside, a key bioactive compound found in plants of the *Swertia* and *Gentiana* genera. This high-purity reference standard is essential for research and development in the pharmaceutical and nutraceutical sectors, where precise chemical characterization is critical. It is primarily sought by analytical laboratories, R&D departments, and manufacturers focused on botanical extracts, hepatoprotective agents, and metabolic health products.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and quality control of herbal medicines and botanical drug substances.
• Hepatoprotective Research: Serves as a key investigational compound in studies targeting liver protection, anti-hepatitis, and anti-fibrotic activities.
• Metabolic Syndrome Studies: Applied in preclinical research for its potential effects on diabetes, obesity, and dyslipidemia.
• Natural Product Isolation & Analysis: Used as a marker compound for the standardization and authentication of extracts from *Swertia* species (e.g., *Swertia chirayita*).
• Dietary Supplement Formulation: Incorporated into high-end nutraceutical products focused on liver support and metabolic health, where standardized actives are required.
• Academic & Institutional Research: Provides a pure compound for pharmacological, phytochemical, and biosynthetic pathway studies in university and government labs.

Basic Information

Product Name	Swertiamarine
CAS No.	17388-39-5
Molecular Formula	C16H22O10
Molecular Weight	374.34 g/mol
Synonyms	Swertiamarin; Swertiamarine; (1S,4aR,5S,7aS)-5-Ethenyl-1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7H-cyclopenta[c]pyran-7-one; Gentiopicrin; Amarogentin related compound; Secologanin aglycone derivative; 7,8-Dihydro-7-(1-hydroxyethyl)swertiamarin; 5-Ethenyl-6-(β-D-glucopyranosyloxy)-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one
EINECS	Contact for details

Quality Control

Our Swertiamarine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While not intended for direct human use as supplied, its quality supports applications requiring reliable and traceable reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.