Description

1-[(4-Methylphenyl)Sulfonyl]Azetidin-3-Yl 4-Methylbenzenesulfonate is a high-purity sulfonate derivative and a key synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular structure, which serves as a versatile building block for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel heterocyclic compounds and sulfonamide-based active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel azetidine-containing drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its sulfonate group for enhanced biological activity and stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of specialized polymers and functional materials requiring sulfonated monomers.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-[(4-Methylphenyl)Sulfonyl]Azetidin-3-Yl 4-Methylbenzenesulfonate
CAS No.	17358-66-6
Molecular Formula	C17H19NO5S2
Molecular Weight	381.47 g/mol
Synonyms	3-Tosyloxy-1-(p-toluenesulfonyl)azetidine; 1-(Tosyl)azetidin-3-yl tosylate; 1-(4-Methylbenzenesulfonyl)azetidin-3-yl 4-methylbenzenesulfonate; Azetidin-3-yl tosylate, 1-tosyl derivative; 3-[(Tosyl)oxy]-1-[(4-methylphenyl)sulfonyl]azetidine; 1-Tosylazetidin-3-yl tosylate; p-Toluenesulfonic acid 1-(p-toluenesulfonyl)-3-azetidinyl ester
EINECS	Contact for details

Quality Control

Our 1-[(4-Methylphenyl)Sulfonyl]Azetidin-3-Yl 4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.