Description

(sec-Butoxymethyl)Trimethylsilane is a specialized organosilicon compound featuring a reactive sec-butoxymethyl group protected by a trimethylsilyl moiety. This unique structure makes it a valuable silylating agent and protected synthon in advanced organic synthesis, particularly for introducing functionalized alkyl groups. It is primarily utilized by pharmaceutical intermediates, agrochemical, and specialty chemical manufacturers who require precise control over molecular architecture.

Application

• Silylation Reagent: Used to introduce the trimethylsilyl (TMS) protecting group onto alcohols, phenols, and carboxylic acids in complex molecule synthesis.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Employed in the production of advanced pesticides, herbicides, and fungicides where specific alkoxyalkyl functionalities are required.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the synthesis of specialty silicones and silane-modified polymers.
• Organic Synthesis Reagent: Utilized in nucleophilic substitution and coupling reactions to construct carbon-carbon and carbon-heteroatom bonds.
• Material Science: Used in surface modification and as a precursor for creating functionalized silanes for coatings and adhesives.

Basic Information

Product Name	(sec-Butoxymethyl)Trimethylsilane
CAS No.	17348-64-0
Molecular Formula	C8H20OSi
Molecular Weight	160.33 g/mol
Synonyms	1-(Trimethylsilyl)methoxybutane; sec-Butyloxymethyltrimethylsilane; Trimethyl(2-butoxymethyl)silane; (2-Butoxymethyl)trimethylsilane; (1-Methylpropoxymethyl)trimethylsilane; sec-Butyl O-(trimethylsilyl)methyl ether; TMS-CH2-O-sec-Bu
EINECS	Contact for details

Quality Control

Our (sec-Butoxymethyl)Trimethylsilane is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.