Description

Bzl-L-2-Aminohexanoic Acid is a protected derivative of the non-proteinogenic amino acid L-norleucine, featuring a benzyl (Bzl) protecting group on the α-amino functionality. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise control over stereochemistry and molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced medicinal chemistry, proteomics research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of peptide-based drugs and bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate modified norleucine residues with a protected amine.
• Proteomics Research: Employed in the study of protein structure-function relationships and the design of enzyme inhibitors or receptor ligands.
• Bioconjugation: Acts as a linker or spacer molecule in the conjugation of peptides to other biomolecules, dyes, or solid supports.
• Chemical Biology Tool: Utilized to probe biological systems and develop novel chemical probes for diagnostic applications.
• Academic & Industrial R&D: Fundamental building block for synthetic chemistry research in universities and corporate R&D laboratories.

Basic Information

Item	Details
Product Name	Bzl-L-2-Aminohexanoic Acid
CAS No.	17345-51-6
Molecular Formula	C₁₃H₁₉NO₂
Molecular Weight	221.30 g/mol
Synonyms	N-Benzyl-L-norleucine; (S)-2-(Benzylamino)hexanoic acid; L-2-(Benzylamino)caproic acid; Bzl-L-Nle-OH; Nα-Benzyl-L-norleucine; N-Bzl-L-Nle; N-Benzyl-L-2-aminohexanoic acid
EINECS	Contact for details

Quality Control

Our Bzl-L-2-Aminohexanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity (HPLC), specific rotation, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Specific Rotation	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.