Description

3-Bromo-6-Methoxypyridazine is a versatile halogenated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its dual functionality, where the bromine atom serves as a reactive site for cross-coupling reactions and the methoxy group can act as a directing group or be further modified. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity intermediates for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with pyridazine cores exhibiting biological activity.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where the pyridazine moiety can contribute to efficacy.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, ligands for catalysis, and functional polymers.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form complex biaryl structures.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes, enzyme inhibitors, and tagged compounds for biological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical and custom synthesis houses serving diverse R&D projects.

Basic Information

Product Name	3-Bromo-6-Methoxypyridazine
CAS No.	17321-29-8
Molecular Formula	C5H5BrN2O
Molecular Weight	189.01 g/mol
Synonyms	6-Methoxy-3-bromopyridazine; 3-Bromo-6-methoxypyridazine; 3-Bromo-6-methoxy-1,2-diazine; Pyridazine, 3-bromo-6-methoxy-; 6-Methoxy-3-bromo-1,2-diazine
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Methoxypyridazine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against established specifications. Certificates of Analysis (COA) documenting all test results are provided and available upon request, supporting compliance in regulated research and manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.