Description

6-Demethoxylnobiletin is a polymethoxyflavone (PMF) derivative, a class of compounds known for their significant biological activity. This high-purity reference standard is critical for research and development in the life sciences, offering a reliable tool for analytical and pharmacological studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutraceutical, and academic sectors for investigating bioactive natural products.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate for studying anti-inflammatory, neuroprotective, and anticancer properties.
• Analytical Chemistry: Used as a certified reference material (CRM) for method development, validation, and quality control in HPLC, LC-MS, and other analytical techniques.
• Nutraceutical & Dietary Supplement Formulation: Investigated as a potential bioactive component in advanced health supplements targeting metabolic and age-related conditions.
• Academic & Institutional Research: Essential for in-vitro and in-vivo studies in universities and research institutes focusing on flavonoid biochemistry and pharmacology.
• Cosmeceutical Development: Explored for its potential antioxidant and skin-protective effects in high-end cosmetic and skincare product research.

Basic Information

Product Name	6-Demethoxylnobiletin
CAS No.	17290-70-9
Molecular Formula	C₂₀H₂₀O₇
Molecular Weight	372.37 g/mol
Synonyms	5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone; 5-Hydroxy-3',4',6,7,8-pentamethoxyflavone; 6-Demethylnobiletin; 6-DMN; NSC 122180; 6-Desmethylnobiletin; 5-Hydroxypentamethoxyflavone
EINECS	Contact for details

Quality Control

Our 6-Demethoxylnobiletin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.