Description

Ethyl 2-(5-Bromobenzo[B]Thiophen-3-Yl)Acetate is a high-purity, synthetic organic compound that serves as a critical advanced intermediate in modern chemical synthesis. Its value lies in the unique benzo[b]thiophene scaffold functionalized with bromine and an ester group, making it a versatile building block for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the brominated thiophene core.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker for developing chemical probes and activity-based protein profiling (ABPP) reagents.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and further functionalization due to the reactive bromine substituent and ester group.

Basic Information

Product Name	Ethyl 2-(5-Bromobenzo[B]Thiophen-3-Yl)Acetate
CAS No.	17266-44-3
Molecular Formula	C₁₂H₁₁BrO₂S
Molecular Weight	299.18 g/mol
Synonyms	Ethyl (5-Bromobenzo[b]thien-3-yl)acetate; 5-Bromo-3-benzo[b]thienylacetic Acid Ethyl Ester; 2-(5-Bromobenzo[b]thiophen-3-yl)acetic Acid Ethyl Ester; Ethyl 5-Bromobenzo[b]thiophene-3-acetate; 5-Bromobenzo[b]thiophene-3-acetic Acid Ethyl Ester; 3-Benzo[b]thienylacetic Acid, 5-Bromo-, Ethyl Ester; Ethyl 2-(5-Bromo-1-benzothiophen-3-yl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(5-Bromobenzo[B]Thiophen-3-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.