Description

(1R,2R)-1β,2α-Cyclopentanedicarboxylic Acid CAS NO 17224-73-6 is a high-purity, stereochemically defined chiral building block of significant importance in asymmetric synthesis. This compound is valued for its rigid, bicyclic structure, which is instrumental in inducing stereoselectivity in complex chemical transformations. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, antiviral agents, and other stereochemically complex drug molecules.
• Asymmetric Catalyst Ligand Precursor: Used to construct chiral ligands for metal-catalyzed reactions, including hydrogenation and cross-coupling.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: Serves as a standard and starting material in methodological development for organic and medicinal chemistry.
• Material Science: Potential monomer for creating polymers with specific chiral or rigid structural properties.

Basic Information

Product Name	(1R,2R)-1β,2α-Cyclopentanedicarboxylic Acid
CAS No.	17224-73-6
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	(1R,2R)-1,2-Cyclopentanedicarboxylic Acid; (1R,2R)-Cyclopentane-1,2-dicarboxylic Acid; (1R,2R)-Norbornane-1,2-dicarboxylic Acid (common misnomer); (1R,2R)-1,2-Dicarboxycyclopentane; endo-1,2-Cyclopentanedicarboxylic Acid (stereospecific); Chiral Cyclopentanedicarboxylic Acid; (1R,2R)-CPDA
EINECS	Contact for details

Quality Control

Our (1R,2R)-1β,2α-Cyclopentanedicarboxylic Acid is manufactured under a strict quality management system. Each batch is analyzed to confirm identity, purity, and enantiomeric excess, ensuring it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, Chiral HPLC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.