Description

Spiro[2.2]Pentane-1-Carboxylic Acid is a unique, highly strained bicyclic carboxylic acid derivative, valued for its rigid three-dimensional spirocyclic framework. This structural motif makes it a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis for creating novel molecular architectures. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for applications requiring precise steric and electronic control.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts due to its rigid, three-dimensional geometry.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal and mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including strain-release functionalization and cycloaddition reactions.

Basic Information

Product Name	Spiro[2.2]Pentane-1-Carboxylic Acid
CAS No.	17202-64-1
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	Spiropentane-1-carboxylic acid; 1-Carboxyspiropentane; Spiro[2.2]pentanecarboxylic acid; Spiro(2.2)pentane-1-carboxylic acid; 1-Spiropentanecarboxylic acid; Bicyclo[1.1.1]pentane-1-carboxylic acid (common misnomer, often used interchangeably); 17202-64-1; Spiro pentane carboxylic acid
EINECS	Contact for details

Quality Control

We supply Spiro[2.2]Pentane-1-Carboxylic Acid in high-purity grades suitable for research and commercial synthesis. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be sensitive to prolonged exposure to heat and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.