Description

3-Ethyl-5-Methylisoxazole-4-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where precise molecular architecture is paramount. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the isoxazole ring's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals requiring specific heterocyclic structures.
• Academic & Industrial Research: A valuable reagent for method development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	3-Ethyl-5-Methylisoxazole-4-Carboxylic Acid
CAS No.	17147-85-2
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	4-Isoxazolecarboxylic acid, 3-ethyl-5-methyl-; 3-Ethyl-5-methyl-1,2-oxazole-4-carboxylic acid; 3-Ethyl-5-methylisoxazole-4-carboxylic acid; 5-Methyl-3-ethylisoxazole-4-carboxylic acid; EMICA; 3-Ethyl-5-methyl-4-isoxazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Ethyl-5-Methylisoxazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.