Description

Nitrofurantoin1-Hydrate is a specific crystalline form of the synthetic nitrofuran antibiotic, nitrofurantoin. This monohydrate form is critical for ensuring consistent stability, solubility, and bioavailability in pharmaceutical manufacturing. It is primarily required by manufacturers in the pharmaceutical and fine chemical sectors for the production of anti-infective medications.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of urinary tract infection (UTI) treatments.
• Pharmaceutical Intermediates in the synthesis of advanced nitrofuran-based drug compounds.
• Reference Standard for quality control and analytical testing in pharmaceutical laboratories.
• Research & Development of new antibacterial agents and drug delivery systems.
• Veterinary Medicine for the development of antibacterial treatments for animals.

Basic Information

Product Name	Nitrofurantoin1-Hydrate
CAS No.	17140-81-7
Molecular Formula	C₈H₆N₄O₅·H₂O
Molecular Weight	258.16 g/mol
Synonyms	Nitrofurantoin Monohydrate; 1-[[(5-Nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione Monohydrate; Furadantin (monohydrate form); (E)-1-[(5-Nitrofurfurylidene)amino]hydantoin Monohydrate; N-(5-Nitro-2-furfurylidene)-1-aminohydantoin Monohydrate; NFH; Nitrofurantoin Hydrate
EINECS	Contact for details

Quality Control

Our Nitrofurantoin1-Hydrate is manufactured under strict quality management systems. It undergoes rigorous analytical testing to meet high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	6.0% - 7.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.