Description

[2S,3S,(-)]-2,3-Dihydroxy-2-Isopropylbutanoic Acid is a high-purity, chiral dihydroxy acid derivative that serves as a critical building block in asymmetric synthesis. Its defined stereochemistry is essential for producing enantiomerically pure compounds, ensuring high efficacy and specificity in advanced applications. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in antiviral and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used to develop and synthesize novel chiral ligands for metal-catalyzed reactions, enhancing stereoselectivity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, agrochemicals, and specialty chemicals requiring specific stereocenters.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway research due to its specific stereoconfiguration.
• Material Science: Potential monomer or modifier for creating polymers with specific chiral properties or for surface functionalization.

Basic Information

Product Name	[2S,3S,(-)]-2,3-Dihydroxy-2-Isopropylbutanoic Acid
CAS No.	17132-48-8
Molecular Formula	C7H14O4
Molecular Weight	162.18 g/mol
Synonyms	(2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid; (-)-2,3-Dihydroxy-2-isopropylbutyric acid; (2S,3S)-2,3-Dihydroxy-3-methylpentanoic acid (isomeric); L-Threo-2,3-Dihydroxy-2-isopropylbutanoic acid; 2-Isopropyl-2,3-dihydroxysuccinic acid (derivative); (2S,3S)-2-(1-Methylethyl)-2,3-dihydroxybutanoic acid; 17132-48-8; (2S,3S)-DIBA
EINECS	Contact for details

Quality Control

Our [2S,3S,(-)]-2,3-Dihydroxy-2-Isopropylbutanoic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity research and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.