Description

Tetrahydro-3-thiophenesulfonyl chloride 1,1-dioxide is a high-purity sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its value lies in its ability to efficiently introduce the sulfonamide or sulfonate functional group, enabling the construction of complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those containing sulfonamide pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides requiring specific sulfonyl-based active ingredients.
• Polymer Chemistry: Serves as a monomer or modifier in the creation of specialty polymers, such as sulfonated polymers for ion-exchange membranes.
• Material Science Research: Employed in developing new organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and labeling of biomolecules.
• Custom Synthesis & Process Development: A versatile reagent for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	Tetrahydro-3-thiophenesulfonyl Chloride 1,1-Dioxide
CAS No.	17115-47-8
Molecular Formula	C4H7ClO2S2
Molecular Weight	186.68 g/mol
Synonyms	3-Thiophenesulfonyl chloride, tetrahydro-, 1,1-dioxide; Tetrahydrothiophene-3-sulfonyl chloride 1,1-dioxide; 3-Sulfolanesulfonyl chloride; Sulfolane-3-sulfonyl chloride; 1,1-Dioxotetrahydrothiophene-3-sulfonyl chloride; 3-Chlorosulfonylsulfolane; NSC 163081
EINECS	Contact for details

Quality Control

Our Tetrahydro-3-thiophenesulfonyl chloride 1,1-dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.